Explore a wide variety of nanoengineered substrates, nano-probes (e.g., quantum dots), and nanoscale imaging techniques for the study of physiological cell behaviors. CINT has the capabilities to grow and maintain prokaryotic (i.e., bacterial) and eukaryotic (e.g., fungal) cells and mammalian cell lines, as well as tissues.
       
Capabilities include:

• RG1 and RG2 material handling, up to BSL-2 requirements & practices.
• Class II, type A2 biosafety cabinets.
• Water-jacketed CO₂ incubator for mammalian cell culture.
• Static and shaking, temperature-controlled incubators.
• Transfection capabilities for plasmid introduction.
• Autoclaves.
• Optical and electron imaging modalities.

For inquiries on the availability of specific organisms and cell lines, please contact:
Dean Morales (Gateway Facility in Los Alamos)
Lisa Phipps  (Gateway Facility in Los Alamos)

Users wishing to bring their own organisms, cell lines, or tissue samples should contact us regarding feasibility, ES&H requirements, and necessary approvals. 

Research Highlights:
Kinesin-Recruiting Microtubules Exhibit Collective Gliding Motion While Forming Motor Trails
Tsitkov, Stanislav, Yuchen Song, Juan B. Rodriguez, Yifei Zhang, and Henry Hess. ACS Nano 2020, 14 (12), 16547–57. doi.org/10.1021/acsnano.0c03263

Combined Chemical and Topographical Guidance Cues for Directing Cytoarchitectural Polarization in Primary Neurons
Greene, Adrienne C., Cody M. Washburn, George D. Bachand, and Conrad D. James. Biomaterials 2011, 32 (34), 8860–69. doi.org/10.1016/j.biomaterials.2011.08.003