Center for Integrated Nanotechnologies

Helping you understand, create, and characterize nanomaterials

2D and 3D Single Molecule and Particle Tracking

Custom 3D tracking microscope via confocal feedback and conventional 2D single molecule tracking via fluorescence microscopy with an EM-CCD camera

Unique in-house developed capabilities in active feedback for time-resolved 3D tracking of single nanoparticles, organic dyes, and fluorescent proteins.

Capabilities include:

Technical Specifications:

Jim Werner
Dean Morales

Research Highlights:
3D Particle Transport in Multichannel Microfluidic Networks with Rough Surfaces
Ryan, D. P.; Chen, Y.; Nguyen, P.; Goodwin, P. M.; Carey, J. W.; Kang, Q.; Werner, J. H.; Viswanathan, H. S. Scientific Reports 2020, 10 (1).

Three-Dimensional Single-Molecule Tracking in Living Cell
Kalb, D. M.; Ryan, D. P.; Morales, D. P.; Goodwin, P. M.; Werner, J. H. Spectroscopy and Dynamics of Single Molecules 2019, 229–267.

Multicolor Three-Dimensional Tracking for Single-Molecule Fluorence Resonance Energy Transfer Measurements
Keller, A. M.; DeVore, M. S.; Stich, D. G.; Vu, D. M.; Causgrove, T.; Werner, J. H. Analytical Chemistry 2018, 90 (10), 6109–6115.

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